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New Research is changing the way we see kidney stone formation.

 "Bad" Bacteria and Kidney Stones  
Of all the forms of bacteria in the world, the very smallest—the tiniest—are known as “nanobacteria.” Like other bacteria, they exist almost everywhere, and recently researchers have identified them in cow and human blood, and in human urine. E. Olavi Kajander and Neva Ciftioglu of the University of Kuopio in Finland recently discovered that these nanobacteria can produce a calcium phosphate mineral layer—called apatite—around themselves, a hard layer similar to bone or tooth enamel. “Nanobacteria are the smallest cell-walled bacteria, only recently discovered in human and cow blood and commercial cell culture serum,'' they wrote in their report in the Proceedings of the National Academy of Sciences.

When they let the serum sit in a test tube for a little while, the bacteria settled on the bottom. They quickly developed a thick shell. Their research suggests that these bacteria may be a possible cause of kidney stones, gall stones, bladder stones, and other similar problems. Depending on circumstances, the nanobacteria may cause the stone covering around themselves or, alternatively, they may produce a biofilm, a sand, or a tumor-like deposit. In certain growth conditions, solid mineral-covered groupings of up to half a centimeter in diameter may grow within just a few weeks.

The researchers found that the mineral coverings over the nanobacteria somewhat resembled bone in structure, but instead of being composed of normal bone matter (hydroxyapatite), they were made of carbonate apatite, the same material most abnormal calcified tissue and stones is made of. In the laboratory research, some of the mineral coverings around small groups of nanobacteria looked exactly like human kidney stones in size and shape. They had a hollow center where small numbers of bacteria could live, completely protected. This similarity led the researchers to look for nanobacteria inside real human kidney stones. Sure enough, they found the bacteria inside all of the 30 stones they looked at. Blood serum itself, they said, contains chemicals that suppress the formation of mineral layers. But they said they had found earlier that nanobacteria can be transported from the blood to the kidneys.

According to the research, the nanobacteria were able to form their stone shelters without the presence of any particular or unusual concentrations of chemicals, and would happily grow in a solution just like urine. The researchers believe that it is very likely that nanobacteria might “seed” kidney stones and mineral deposits in the joints and tendons that can lead to certain types of arthritis, pseudogout and joint inflammation. Nanobacterial deposits might also cause atherosclerotic plaques (fatty deposits inside the arteries) to accumulate calcium phosphate, as well as contributing to mineralization of certain tumors, an unexplained condition often suffered by dialysis patients.

Information for this article was taken from Macmillan Magazines Ltd
1998, NATURE NEWS; and Reuters News Service, Washington.


How can you deal with this bacteria? Click here


Helpful Bacteria and Kidney Stones

Researchers have recently found that calcium oxalate stones form in people who lack a certain beneficial bacteria. They tried a number of different things to get it back, but enzyme therapy was the only effective supplement.
Click Here to read this exciting new research about enzyme therapy and kidney stones.





This information is not intended to diagnose, treat, cure or prevent any disease.
If you need medical attention, consult your health care professional.